Monthly Archives: August 2014

grinderbot: Lab grown thymus Lab-grown replacement organs have…


Lab grown thymus

Lab-grown replacement organs have moved a step closer, thanks to a major breakthrough by researchers at the University of Edinburgh, Scotland. Scientists have for the first time grown a complex, fully-functional organ from scratch in a living animal by transplanting cells that were originally created in a laboratory. The researchers created a thymus – an organ next to the heart that produces immune cells known as T cells that are vital for guarding against disease. With further research, this discovery could lead to new treatments for elderly patients and others with a weakened immune system.

The team from the MRC Centre for Regenerative Medicine at the University of Edinburgh took cells called fibroblasts from a mouse embryo. They turned the fibroblasts into a completely different type of cell called thymus cells, using a technique called reprogramming. The new cells changed shape to look like thymus cells and were also capable of supporting development of T cells in the lab – a specialised function that only thymus cells can perform.

When the researchers mixed reprogrammed cells with other key thymus cell types and transplanted them into a live mouse, the cells formed a replacement organ. This new organ had the same structure, complexity and function as a healthy adult thymus. It is the first time that scientists have made an entire living organ from cells that were created outside of the body by reprogramming.

tinycartridge: Happy 20th anniversary, Earthbound! ⊟ The SNES…


Happy 20th anniversary, Earthbound! ⊟

The SNES RPG released 20 years ago today in Japan, where it came out as Mother 2. Where did all those years go? Why isn’t there an English portable version of this? How am I going to justify buying a Mr. Saturn haramaki?

The series’ creator Shigesato Itoi posted this message today:

It’s been 20 years now since MOTHER 2 came out.

…Are you happy?

・Yes → Me too.

・No → Be happy!!

Thanks to @pimoji for the anniversary photo and artwork.

BUY Mother 3/Earthbound, Hobonichi Techo, upcoming games